Also known as: Fe, Ferrous iron
Iron is an essential trace element required for oxygen transport, energy metabolism, and DNA synthesis. It is a key component of hemoglobin and myoglobin and is one of the most common nutritional deficiencies worldwide.
Iron is a critical mineral that exists in two dietary forms: heme iron (from animal sources) and non-heme iron (from plant sources and supplements). Approximately 70% of body iron is found in hemoglobin, where it enables red blood cells to carry oxygen from the lungs to tissues throughout the body. Iron also supports mitochondrial energy production, immune function, and cognitive development. Iron deficiency is the most prevalent nutritional deficiency globally, affecting an estimated 1.6 billion people and leading to anemia, fatigue, impaired cognitive function, and weakened immunity. However, iron is unique among minerals in that the body has no regulated excretion mechanism, making excess accumulation potentially toxic. Supplementation should be guided by documented deficiency or elevated need, such as during pregnancy or heavy menstrual blood loss.
Iron supplementation restores hemoglobin levels and alleviates symptoms of fatigue, weakness, and cognitive impairment associated with iron-deficiency anemia.
Iron is essential for neurotransmitter synthesis and myelination. Correcting iron deficiency improves attention, memory, and learning capacity, particularly in children and adolescents.
On an empty stomach or with vitamin C for enhanced absorption
Alternate-day dosing (every other day) may improve absorption and reduce side effects.
With a meal to reduce GI upset
Premenopausal women, vegetarians, and frequent blood donors are at higher risk of deficiency.
Best tolerated form with fewer GI side effects
Standard clinical treatment of iron deficiency
Thorne
Solgar
Nature Made
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